Virulence: An Infectious Card Game
BGG rank
BGG #8,083
BGG rating
6.6

Virulence: An Infectious Card Game

2016

Rules assistance for Virulence: An Infectious Card Game

Plain-language explanations of turns, card effects and disputed situations, with official source references and saved question history.

  • 2–5 players
  • 10–20 min
  • 8+
  • Complexity 1.6/5

For 2 players

Rules assistant for Virulence: An Infectious Card Game

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Answers come from the official rulebook, with the page to check.

Virulence: An Infectious Card Game is a board game released in 2016 for 2–5 players, 10–20 minutes per game, and ages 8 and up. It was designed by John Coveyou and Paul Salomon and its main mechanics are Variable Player Powers, Hand Management, and Set Collection.

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About the game

Virulence: An Infectious Card Game is an addictively quick and simple card game focused on viruses infecting a host cell - and how they assemble and replicate inside that host cell. Virulence has players take on the role of viruses competing to infect a host cell in order to replicate their own viral components, thus scoring points. Each round, players secretly choose one Virus card from their hand, place it face down on the table, then simultaneously flip these Virus cards to reveal each player's (and thus each virus') virulence. In order from the highest to the lowest virulence, players then take turns selecting from the available Viral Component cards, each awarding points in a variety of ways, or allowing that player to build their hand of Virus Cards allowing them to win critical components later. Virulence is addictively simple and competitive because it combines blind bidding/bluffing, with engine building, a bit of luck and, most importantly, it can played be taught in 30 seconds, and played 10 minutes.

Questions and answers

Virulence: An Infectious Card Game supports 2–5 players according to the catalogue. This range comes from the publisher’s listed player count, so the game can be set up for any group size within it. Some setups, rules and scoring details may still vary by player count, so check your edition’s rulebook for the exact configuration.